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Two Cases of Graves’ Disease Presented with Atypical Symptoms
Int J Thyroidol 2016;9(2):174-179
Published online November 30, 2016;  https://doi.org/10.11106/ijt.2016.9.2.174
© 2016 Korean Thyroid Association.

Won Sang Yoo and Hyun Kyung Chung

Department of Internal Medicine, Dankook University Medical College, Cheonan, Korea
Correspondence to: Hyun Kyung Chung, MD, PhD, Department of Internal Medicine, Dankook University Hospital, 16-5 Anseo-dong San, Cheonan 31116, Korea
Tel: 82-41-550-7664, Fax: 82-41-556-0524, E-mail: chkendo@dankook.ac.kr
Received May 3, 2016; Revised May 26, 2016; Accepted June 1, 2016.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
We describe here two Graves’ patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old woman (case 1) was the ipsilateral edema of upper body. A 33-year-old man (case 2) who had severe polyuria has referred from urology department with impression of diabetes insipidus. Both of them denied any typical symptoms of Graves’ disease at presentation. These rare extrathyroid manifestations of Graves’ disease were completely subsided after antithyroid drug treatment. We introduce their clinical courses and possible pathophysiological mechanisms of the atypical symptoms of Graves’ disease.
Keywords : Graves’ disease, Edema, Polyuria

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