Clinicopathological characteristics of the 41 anaplastic thyroid carcinoma patients who underwent
| Variable | Number of patients (%) | |||
|---|---|---|---|---|
| Total (n=41) | Wild (n=26) | p value | ||
| Age, years | 68.9 (42.1-91.0) | 65.0 (49.6-81.1) | 71.0 (42.1-91.0) | 0.437 |
| Sex, female | 25 (61.0) | 8 (53.3) | 17 (65.4) | 0.667 |
| Concurrent DTC | 0.044 | |||
| No DTC | 15 (36.6) | 2 (13.3) | 13 (50.0) | |
| With DTC | 26 (63.4) | 13 (86.7) | 13 (50.0) | |
| Stage | 0.478 | |||
| IVA | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| IVB | 18 (43.9) | 5 (33.3) | 13 (50.0) | |
| IVC | 23 (56.1) | 10 (66.7) | 13 (50.0) | |
| Tumor size, cm | 4.9 (0.8-11.0) | 5.1 (3.0-11.0) | 4.2 (0.8-8.0) | 0.010 |
| Lymph node metastasis | 33 (80.5) | 11 (73.3) | 22 (84.6) | 0.639 |
| Distant metastasis | 23 (56.1) | 10 (66.7) | 13 (50.0) | 0.478 |
| Surgery | 29 (70.8) | 13 (86.7) | 16 (61.5) | 0.232 |
| Treatment | 0.056 | |||
| Aggressive | 13 (31.7) | 8 (53.3) | 5 (19.2) | |
| Non-aggressive | 28 (68.3) | 7 (46.7) | 21 (80.8) | |
Data are presented as median (range) or number (percentage).
DTC: differentiated thyroid carcinoma,
The aggressive treatment group consisted of patients who underwent surgery, external radiotherapy, and systemic therapy. The non-aggressive treatment group consisted of patients who received one or two of the therapy types: surgery, radiotherapy, and systemic therapy.