Fig. 3. Core needle biopsy (CNB) of a large isoechoic nodule with thick rim macrocalcification. (A) A 83-year-old female patient presented with a large isoechoic nodule (21×24×25 mm) on the left side of the thyroid with thick rim macrocalcification with prominent posterior acoustic shadowing. (B) Since macrocalcification had enough clearance from the left common carotid artery and trachea, hydrodissection was not performed. Trans-isthmic approach of CNB needle was performed. (C) The mammography demonstrated normalized SI of calcification (arrow) as 2.0, while non-calcified portion as 1.3. The pathology confirmed it as probable benign nodule with hyalinized stroma with calcification and focal area of macrofollicular proliferation.
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