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Comparison of the clinico-pathological characteristics between the high
| Characteristics | NCOR1/THRA n=24 (%) | SMRT/THRB n=24 (%) | p-value |
|---|---|---|---|
| Age (years) | 48.36±14.56 | 52.78±16.98 | 0.356 |
| Gender (Male:Female) | 3 (12.5):21 (87.5) | 10 (41.7):14 (58.3) | 0.023 |
| Tumor size (cm) | 2.68±1.50 | 3.02±1.38 | 0.475 |
| MACIS score | 5.16±1.24 | 6.05±2.01 | 0.097 |
| Histologic subtype | 0.172 |
||
| Follicular variant | 4 (18.2) | 1 (4.3) | |
| Conventional | 17 (77.3) | 18 (78.3) | |
| Tall cell variant | 0 (0.0) | 4 (17.4) | |
| Others |
1 (4.5) | 0 (0.0) | |
| Extrathyroidal extension | 0.028 |
||
| No | 19 (82.6) | 12 (52.2) | |
| Yes | 4 (17.4) | 11 (47.8) | |
| Multifocality | 0.555 |
||
| No | 11 (47.8) | 13 (56.5) | |
| Yes | 12 (52.2) | 10 (43.5) | |
| T stage | 0.038 |
||
| T1 | 9 (39.1) | 3 (13.0) | |
| T2 | 7 (30.4) | 7 (30.4) | |
| T3 | 6 (26.1) | 11 (47.8) | |
| T4 | 1 (4.3) | 2 (8.7) | |
| N stage | 0.001 |
||
| N0 | 17 (81.0) | 7 (31.8) | |
| N1 | 4 (19.0) | 15 (68.2) | |
| M stage | 0.309 |
||
| M0 | 14 (100.0) | 13 (92.9) | |
| M1 | 0 (0.0) | 1 (7.1) | |
| TNM stage | 0.038 |
||
| I | 14 (63.6) | 9 (39.1) | |
| II | 3 (13.6) | 2 (8.7) | |
| III | 4 (18.2) | 7 (30.4) | |
| IV | 1 (4.5) | 5 (21.7) |
*p-values calculated using Student’s t-test. Data are mean±SD.
†p-values calculated using χ2 test or linear-by-linear association.
ςOthers: columnar cell variant, diffuse sclerosing variant, cribriform-morular variant, etc.