International Journal of Thyroidology

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Table. 1.

Table. 1.

A list of studies reported on clinical outcome, recurrence rates, and complication rates after lateral neck dissection

Study name (reference number) Year Follow up time (month) Range of lateral neck dissection (patient number) Methods to identify metastatic LN Clinical outcome Recurrence rate Complication rate
McNamara et al.24) 2016 Median 63.5 CND: IIa-Ⅴb±IIb, Ⅴa ND (364) SND: III-IV±II (120) Macroscopic in operation, US, CT Overall recurrence-free probability 94.4%:89.4% (p=0.158) Dissected neck field recurrence-free probability 97.7%:89.4% (p<0.01) Total recurrence rate 27/364:11/120 (7.4%:9.2%) Ipsilateral recurrence rate 3%/9% (p<0.05) Hematoma 5/364:2/120 (1.4%:1.7%) Shoulder syndrome 23/364:0/120 (6.3%:0%) (p=0.019) Chyle leak 5/364:2/120 (1.4%:1.7%)
Turanli25) 2007 Median 57.5:72 CND: I-Ⅴ (32) SND: II-IV (29) US (FNAB) Overall survival 58 m:73 m (p=0.33) Disease free survival 54 m:56 m (p=0.92) 7/32:9/29 (21.9%/31%) (p=0.56) Not reported
Strajina et al.26) 2019 Median 64±48 CND: IIa-Vb (102) SND: less extensive dissection (143) US Not reported 12/102:31/143 (12%/22%) (p=0.04) Total complication 11/102/:7/143 (11%/5%) (p=0.08) Marginal mandibular palsy/shoulder dysfunction 2/102:0/143 (2%/0%) (p=0.09)
Kim et al.19) 2017 Median 53.4 CND: II-V (263) SND: II-IV (263) US (FNAB), CT Not reported Not reported Hematoma 0/263:1/263 (0%:0.4%) Shoulder syndrome 24/263:7/263 (9.1%:2.7%) (p=0.002) Chyle leak 5/263:1/263 (1.9%:0.4%)
Javid et al.27) 2016 Median 14.3 CND: II-V (195) SND: II-IV (4) III-IV (2) IV (1) US (FNAB) Not reported 15/195:NR (7.6%:NR) Permanent RLN palsy 0/195:-/- (0%:-) Shoulder syndrome 3/195:-/- (1.5%:-) Horner syndrome 0.195:-/- (0%:-) Chyle leak 2/195:-/- (1.0%:-)
Kupferman et al.28) 2004 Not reported CND: II-V (44) US, CT, MRI Not reported Not reported Permanent RLN palsy 2/44 (4.5%) Hematoma 0/44 (0%) Shoulder syndrome 12/44 (27%) Chyle leak 2/44 (4.5%)

CND: comprehensive neck dissection, CT: computed tomography, FNAB: fine needle aspiration biopsy, LN: lymph node, MRI: magnetic resonance imaging, ND: neck dissection, RLN: recurrent laryngeal nerve, SND: selective neck dissection, US: ultrasonography

Int J Thyroidol 2021;14:81-6 https://doi.org/10.11106/ijt.2021.14.2.81
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