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Anaplastic Transformation of Follicular Thyroid Cancer in the Lung, Liver, Bone, and Adrenal Gland
Int J Thyroidol 2017;10(2):127-132
Published online November 30, 2017;
© 2017 Korean Thyroid Association.

Wonae Lee1 and Dohee Kim2,3

Departments of Pathology1, Internal Medicine2, Dankook University College of Medicine, Department of Kinesiologic Medical Science, Graduate, Dankook University3, Cheonan, Korea
Correspondence to: Dohee Kim, MD, PhD, Division of Endocrinology, Department of Internal Medicine, Dankook University College of Medicine, 119 Dandae-ro, Dongnam-gu, Cheonan 31116, Korea
Tel: 82-41-550-3934, Fax: 82-41-556-3256, E-mail:
Received August 2, 2017; Revised November 6, 2017; Accepted November 10, 2017.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Anaplastic transformation of differentiated thyroid cancer at distant metastatic sites is extremely rare and has a poor prognosis. It usually occurs in the thyroid gland or cervical lymph nodes. Here we report a case of anaplastic transformation arising at multiple distant metastatic sites including the lung, liver, adrenal gland, bone, and lymph nodes in a patient 3 years after total thyroidectomy for follicular thyroid cancer.
Keywords : Cell transformation, Neoplastic, Thyroid carcinoma, Anaplastic, Thyroid cancer, Follicular, Thyroid cancer, Papillary

November 2018, 11 (2)