search for


Primary Sclerosing Mucoepidermoid Carcinoma with Eosinophilia of the Thyroid: Description of a Case and Review of the Literature
Int J Thyroidol
Published online October 10, 2017
© 2017 Korean Thyroid Association.

Song I Yang1, Kwang Kuk Park2 and Ji Young Yoo1

Department of Surgery, Kosin University College of Medicine1, Department of Surgery, Hub-Hu Hospital2, Busan, Korea
Correspondence to:

Song I Yang, MD, PhD

Department of Surgery, Kosin University College of Medicine, 262 Gamcheonro, Seo-gu, Busan 49267, Korea
Tel: 82-51-990-6462, Fax: 82-51-246-6093, E-mail:

Received April 17, 2017; Revised June 27, 2017; Accepted July 3, 2017.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Primary sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland is a very rare disease. We present the clinical and histopathologic findings of a 37-year-old woman recently diagnosed with SMECE of the thyroid gland. The patient, clinically euthyroid, who presented with a neck swelling since last 2 years along. Fine needle aspiration cytology suggested thyroid papillary carcinoma. Total thyroidectomy, central neck dissection and right selective neck dissection were performed. Although SMECE is considered to be a relatively slow growing and non-aggressive tumor, occasional metastasis does occur. We report an additional case of SMECE, with metastasis to regional lymph nodes. Physicians should be aware of extended operation, including total thyroidectomy and/or neck node dissection for metastatic lesion of the neck node. More standardized treatment is likely to evolve in the future.
Keywords : Mucoepidermoid, Carcinoma, Eosinophilia, Thyroid gland