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Epidemiologic Association between Obesity and Thyroid Nodules
Int J Thyroidol 2017;10(1):1-4
Published online May 30, 2017;
© 2017 Korean Thyroid Association.

Hwa Young Ahn

Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
Correspondence to: Hwa Young Ahn, MD, Department of Internal Medicine, Chung-Ang University College of Medicine, Heukseok-ro 102, Dongjak-gu, Seoul 06973, Korea
Tel: 82-2-6299-3152, Fax: 82-2-6299-2017, E-mail:
Received October 11, 2016; Revised April 27, 2017; Accepted April 27, 2017.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Recently, the incidence of thyroid nodule has been rising due to the usage of ultrasonography in health check-up. Also, modern society is faced with increasing rates of obesity by sedentary life style and high caloric intake. Obesity is closely related to metabolic syndrome and insulin resistance. Insulin resistance leads to hyperinsulinemia, increased insulin-like growth factor 1 and alteration of adipocytokine level. These factors not only have a role in metabolic regulation, but they also have mitogenic effect in cell proliferation. Epidemiologic and clinical evidence about the association between obesity and thyroid nodule are reviewed in this section.
Keywords : Thyroid nodules, Obesity, Insulin resistance, Metabolic syndrome X