International Journal of Thyroidology

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Table. 5.

Table. 5.

Clinicopathological characteristics of RCC in patient with coexisting primary TC and RCC

RCC characteristics Both TC and RCC

Totaln=53 RCC → TCn=24 TC=RCCn=12 TC → RCCn=17 p value
Tumor size, cm (range) 3.7 (0.9-16.0) 3.9 (1.7-16.0) 2.7 (1.3-7.0) 4.5 (0.9-13.0) 0.186
Bilaterality 2 (3.8) 2 (8.3) 0 (0) 0 (0) 0.493
Pathologic stage* 0.744
Stage 1 41 (77.4) 17 (70.8) 11 (91.7) 13 (76.5)
Stage 2 2 (3.8) 2 (8.3) 0 (0) 0 (0)
Stage 3 7 (13.2) 4 (16.7) 1 (8.3) 2 (11.8)
Stage 4 3 (5.7) 1 (4.2) 0 (0) 2 (11.8)
LN metastasis 1 (1.9) 1 (4.2) 0 (0) 0 (0) 1.000
Distant metastasis 3 (5.7) 1 (4.2) 0 (0) 2 (11.8) 0.449
Nuclear grade 0.060
Gr 1-2 21 (42.0) 13 (56.5) 5 (45.5) 3 (18.8)
Gr 3-4 29 (58.0) 10 (43.5) 6 (54.5) 13 (81.3)
Operation type 0.348
Radical nephrectomy 31 (58.5) 16 (66.7) 5 (41.7) 10 (58.8)
Nephron sparing surgery 22 (41.5) 8 (33.3) 7 (58.3) 7 (41.2)
Vascular invasion 2 (3.8) 0 (0) 1 (8.3) 1 (5.9) 0.295
Collecting system invasion 1 (1.9) 0 (0) 0 (0) 1 (5.9) 0.547
Histologic subtype 0.772
Clear cell 50 (94.3) 23 (95.8) 12 (100) 15 (88.2)
Renal papillary carcinoma 1 (1.9) 0 (0) 0 (0) 1 (5.9)
Chromophobe 2 (3.8) 1 (4.2) 0 (0) 1 (5.9)

Gr: grade, LN: lymph node, RCC: renal cell carcinoma, TC: thyroid cancer

*Staging according to the American Joint Committee on Cancer (AJCC) Kidney Cancer Staging System 7th edition.

Int J Thyroidol 2021;14:28-36 https://doi.org/10.11106/ijt.2021.14.1.28
© 2021 Int J Thyroidol