International Journal of Thyroidology

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Table. 4.

Table. 4.

Clinicopathological characteristics of TC in patient with coexisting primary TC and RCC

TC characteristics Both TC and RCC

Totaln=53 RCC → TCn=24 TC=RCCn=12 TC → RCCn=17 p value
Tumor size, cm (range) 0.9 (0.2-4.0) 1.0 (0.2-4.0) 1.2 (0.4-4.0) 0.8 (0.5-3.0) 0.396
Multifocality 24 (45.3) 12 (50.0) 6 (50.0) 6 (35.3) 0.604
Bilaterality 18 (34.0) 10 (41.7) 4 (33.3) 4 (23.5) 0.525
Pathologic stage* 0.572
Stage 1 19 (35.8) 6 (25.0) 6 (50.0) 7 (41.2)
Stage 2 0 (0) 0 (0) 0 (0) 0 (0)
Stage 3 30 (56.6) 16 (66.7) 5 (41.7) 9 (52.9)
Stage 4 4 (7.5) 2 (8.3) 1 (8.3) 1 (5.9)
LN metastasis 23 (43.4) 10 (41.7) 7 (58.3) 6 (35.3) 0.455
Distant metastasis 1 (1.9) 0 (0) 1 (8.3) 0 (0) 0.226
Operation type 0.845
TT w/ or w/o CND 42 (79.2) 20 (83.3) 8 (66.7) 14 (82.4)
TT with MRND 4 (7.5) 1 (4.2) 1 (8.3) 2 (11.8)
Lobectomy 7 (13.2) 3 (12.5) 3 (25.0) 1 (5.9)
Extrathyroidal extension 32 (60.4) 16 (66.7) 6 (50.0) 10 (58.8) 0.628
Lymphatic invasion 0 (0) 0 (0) 0 (0) 0 (0)
Vascular invasion 0 (0) 0 (0) 0 (0) 0 (0)
Histologic subtype 0.558
PTC 49 (92.5) 22 (91.7) 11 (91.7) 16 (94.1)
FTC 3 (5.7) 2 (8.3) 1 (8.3) 0 (0)
MTC 1 (1.9) 0 (0) 0 (0) 1 (5.9)
RAI therapy 39 (73.6) 17 (70.8) 7 (58.3) 15 (88.2) 0.260
Initial RAI dose, mCi (range) 100 (30-180) 60 (30-150) 100 (30-180) 30 (30-150) 0.478
Total RAI dose, mCi (range) 100 (30-550) 60 (30-280) 130 (30-550) 100 (30-450) 0.520

CND: central neck dissection, FTC: follicular thyroid cancer, LN: lymph node, MRND: modified radical neck dissection, MTC: medullary thyroid cancer, PTC: papillary thyroid cancer, RAI: radioactive iodine, RCC: renal cell carcinoma, TC: thyroid cancer, TT: total thyroidectomy, w/: with, w/o: without

*Staging according to the American Joint Committee on Cancer (AJCC) Thyroid Cancer Staging System 7th edition.

Int J Thyroidol 2021;14:28-36 https://doi.org/10.11106/ijt.2021.14.1.28
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