International Journal of Thyroidology

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Table. 2.

Table. 2.

Clinical characteristics of 707 lymph nodes (LNs) according surgery status and final outcome

Characteristics Preoperative LNs (n=295) Postoperative LNs (n=412) p value


Metastatic Benign Metastatic Benign
LNs (n, %) 91 (30.8) 204 (69.2) 123 (29.9) 289 (70.1)
US finding* 0.572
Suspicious (n, %) 59 (64.8) 31 (15.1) 63 (51.2) 49 (17.0)
Intermediate (n, %) 25 (27.5) 124 (60.8) 48 (39.0) 175 (60.6)
Benign (n, %) 7 (7.7) 49 (24.1) 12 (9.8) 65 (22.4)
Serum Tg (ng/mL) 35.8±66.5(0.1-461.7) 37.0±100.1(0.0-753.5) 20.6±83.0(0.0-868.2) 12.1±83.0(0.0-805.7) 0.002
Serum TgAb (IU/mL) 91.8±170.4(3.4-750.6) 111.4±674.8(0.1-6480.7) 59.6±295.7(0.1-1896.7) 37.4±200.5(0.1-2826.6) 0.008
Washout Tg (ng/mL) 574.7±366.1(0.0-1251.7) 26.4±122.6(0.0-1002.4) 485.5±396.4(0.0-1248.5) 35.0±152.6(0.0-1074.0) 0.088
Washout Tg/serum Tg ratio 138.8±1366.5(0.0-14307.3) 194.6±568.9(0.0-4309.6) 1479.8±4095.5(0.0-29802.3) 545.6±6757.6(0.0-11277.3) 0.001
Discordant results between FNAC and washout Tg (n, %) 16 (17.6) 29 (9.8) 26 (21.1) 35 (12.1) 0.321

Data are expressed as median (range) or number including percentage.

FNAC: fine needle aspiration cytology, Tg: thyroglobulin, TgAb: thyroglobulin antibody, US: ultrasonography

*US finding.

Suspicious; micro/macrocalcification, hyperechogenicity, cystic change, and abnormal vascularity.

Intermediate; loss of central hilar echo and absence of central hilar vascularity.

Benign; central hilar echo, central hilar vascularity.

Int J Thyroidol 2021;14:18-27 https://doi.org/10.11106/ijt.2021.14.1.18
© 2021 Int J Thyroidol