International Journal of Thyroidology

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Table. 4.

Table. 4.

Multivariate analysis according to TPOAb positivity in total and male, female subjects

Total Male Female




OR (CI) p value OR (CI) p value OR (CI) p value
Sex <0.001
Male 1 - -
Female 2.12 (1.51-2.98) - -
Age <0.001 0.038 0.001
10-19 1 1 1
20-29 2.53 (0.66-9.67) 1.94 (0.77-4.88) 1.37 (0.68-2.76)
30-39 2.67 (0.70-10.24) 1.50 (0.58-3.89) 1.99 (0.93-4.26)
40-49 3.88 (1.02-14.69) 1.82 (0.77-4.27) 3.22 (1.45-7.17)
50-59 5.94 (1.60-22.03) 2.91 (1.20-7.07) 4.67 (2.11-10.34)
60-69 4.74 (1.24-18.13) 3.41 (1.49-7.77) 3.18 (1.38-7.34)
≥70 1.17 (0.22-6.21) 0.90 (0.17-4.85) 0.82 (0.16-4.29)
Thyroid disease <0.001 <0.001 <0.001
No 1 1 1
yes 7.46 (4.86-11.46) 39.42 (12.33-126.02) 5.58 (3.51-8.88)
TSH <0.001 <0.001 <0.001
<0.35 1.59 (0.65-3.89) 4.05 (1.01-16.24) 1.45 (0.55-3.83)
0.35-5.5 1 1 1
>5.5 4.00 (2.75-5.81) 4.29 (2.18-8.47) 3.42 (2.30-5.10)
fT4 0.024 0.003 0.079
<0.89 2.22 (1.18-4.17) 6.22 (2.14-18.14) 1.76 (0.88-3.52)
0.89-1.76 1 1 1
>1.76 2.53 (0.81-7.91) 1.64 (0.29-9.33) 3.79 (0.91-15.89)
UIC 0.102 0.245 0.098
<100 1 1 1
100-199 0.77 (0.50-1.16) 0.72 (0.35-1.46) 0.79 (0.49-1.29)
200-299 0.61 (0.38-0.97) 0.66 (0.30-1.46) 0.63 (0.37-1.07)
300-599 0.68 (0.43-1.07) 0.46 (0.20-1.07) 0.80 (0.50-1.30)
600-999 0.49 (0.28-0.84) 0.35 (0.12-1.05) 0.57 (0.32-1.01)
≥1000 0.60 (0.38-0.96) 0.92 (0.40-2.09) 0.51 (0.30-0.85)

CI: 95% confidence interval, fT4: free T4, OR: odd ratio, TPOAb: thyroid peroxidase antibody, TSH: thyroid stimulating hormone, UIC: urinary iodine concentration

Int J Thyroidol 2020;13:155-64 https://doi.org/10.11106/ijt.2020.13.2.155
© 2020 Int J Thyroidol