International Journal of Thyroidology

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Table. 3.

Table. 3.

Percutaneous ethanol ablation (EA) results

Total No post-EA RAI treatment Post-EA RAI treatment
Patients (n) 42 23 19
Number of lesions 71 32 39
Follow-up, months (mean±SD) 40.50±18.01 41.76±19.43 38.65±16.83
Number of EAs 169 74 95
Per lesion (mean±SD) 2.38±1.26 2.31±1.12 2.43±1.31
Per patient 4.02 3.21 5.0
Ethanol volume
Per procedure, mL (mean±SD) 0.82±0.65 0.80±0.58 0.84±0.75
Per lesion, mL (mean±SD) 1.95±1.32 1.85±1.15 2.04±1.44
Volume reduction (%) (mean±SD) 84.82±26.10% 86.66±28.04% 83.32±24.52%
Lesions with >50% volume reduction, % (n) 97.18% (67) 96.87% (31) 97.43% (38)
Lesions with loss of Doppler signal, % (n) 87.32% (62) 87.5% (28) 87.17% (34)
Lesions with Tg<1 ng/mL in FNA washout, % (n) 91.54% (65) 93.75% (30) 89.74% (35)
Lesions with full response, % (n) 87.32% (62) 87.5% (28) 87.17% (34)
Lesions completely disappeared, % (n) 67.60% (48) 71,87% (23) 64,10% (25)
Recurrent EA treated lesions, % (n) 5.63% (4) 3.12% (1) 7.69% (3)
New recurrent disease in EA treated patients % (n) 16.66% (7) 8.69% (2) 26.31% (5)*
% patients with adverse events
Moderate to severe persistent pain % (n) 30.95% (13) 26.08% (6) 36.84% (7)
Transient recurrent nerve injury % (n) 7.14% (3) 4.34% (1) 10.52% (2)

FNA: fine needle aspiration, RAI: radioactive iodine, SD: standard deviation

A successful EA procedure was considered when all >50% volume reduction, loss of Doppler signal and Tg <1 ng/dL in FNA washout were achieved in each treated lesion.

*p<0.05 (Chi-square test)

Int J Thyroidol 2020;13:128-41 https://doi.org/10.11106/ijt.2020.13.2.128
© 2020 Int J Thyroidol